|
KMID : 0371320020630010023
|
|
Journal of the Korean Surgical Society
2002 Volume.63 No. 1 p.23 ~ p.29
|
|
|
Preoperative Localization in Primary Hyperparathyroidism Comparison of Tc99m MIBI Scan and Tl201/Tc99m Subtraction Scan
|
|
Kang Kyung-Ho
Chang Myung-Chul
Roh Dong-Young
Youn Yeo-Kyu
Moon Byung-In
Oh Seung-Keun
|
|
|
Abstract
|
|
|
Purpose: Recently Tc99m MIBI (methoxyisobutylisonitrile) has been described as an alternative to thallium for localizing parathyroid lesions. The purpose of this study was to compare the efficacy of a Tc99m MIBI scan
with a
Tl201/Tc99m subtraction scan for localizing parathyroid lesions in patients with primary hyperparathyroidism.
Methods: Among 31 cases of primary hyperparathyroidism operated on at the Department of Surgery, Seoul National University Hospital from January 1997 to June 2001, a Tl201/Tc99m subtraction scan was performed on 16
patients
and a Tc99m MIBI scan on 22 patients. Seven patients underwent both.
Results: The pathology was a single adenoma in 28 patients, a hyperplasia in 1 patient and a carcinoma in 2 patients. Hypercalcemia was controlled postoperatively in all cases. The sensitivities of the Tl201/Tc99m
subtraction scan and Tc99m MIBI scan were 53.3% and 86.4%, respectively. The positive predictive values were 100% of the two study groups.
Conclusion: We concluded that the better accuracy, superior image quality and lower cost of Tc99m MIBI scan will make it the new radiopharmaceutical parathyroid scan of choice. A unilateral approach can be used with a high degree
of
success, as in case of a preoperatively localized single parathyroid adenoma, which was confirmed when surgical exploration identified of a normal ipsilateral gland.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
  
|